Extranodal Natural Killer/T-Cell Lymphoma presenting with Recurrent Nasal Vestibulitis: A Case Report

Authors

  • Bikash Gurung Department of ENT Head & Neck Studies , Pokhara Academy of Health Sciences, Pokhara, Nepal
  • Urmila Gurung Department of ENT Head & Neck Studies, Tribhuvan University Teaching Hospital, Institute of Medicine, Maharajgunj, Kathmandu, Nepal
  • Nar Maya Thapa Department of ENT Head & Neck Studies, Tribhuvan University Teaching Hospital, Institute of Medicine, Maharajgunj, Kathmandu, Nepal
  • Bibhu Pradhan Department of ENT Head & Neck Studies, Tribhuvan University Teaching Hospital, Institute of Medicine, Maharajgunj, Kathmandu, Nepal
  • Anjan Shrestha Department of Medicine, Tribhuvan University Teaching Hospital, Institute of Medicine, Maharajgunj, Kathmandu, Nepal
  • Shreya Shrivastav Department of Pathology, Tribhuvan University Teaching Hospital, Institute of Medicine, Maharajgunj, Kathmandu, Nepal

Keywords:

Extra-nodal NK/T-cell lymphoma, Epstein-Barr virus (EBV), LVP regimen, recurrent nasal vestibulitis

Abstract

Extranodal NK/T-cell lymphoma, nasal type is a rare lymphoid neoplasm, which is aggressive non-Hodgkin’s type, grouped with a variety of granulomatous diseases in the past. It commonly involves the sinonasal tract leading to destruction of the midline structures of face. Its histological diagnosis can be difficult because of extensive tissue necrosis and has an ominous prognosis.This case report is of a middle-aged woman who presented with recurrent right nasal vestibulitis, mimicking as nasal granulomatosis. Immunohistochemistry confirmed that it was ENKL of nasal cavity. She attained complete remission with L-asparaginase, vincristine, prednisolone regimen with sandwiched radiotherapy. The vague presentation is one of the causes of delayed diagnosis for this type of condition. Radiological imaging along with histopathological examination with immunohistochemistry is essential for early diagnosis.

Keywords: Extra-nodal NK/T-cell lymphoma, Epstein-Barr virus, LVP regimen, recurrent nasal vestibulitis

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Published

2026-07-30

How to Cite

1.
Gurung B, Gurung U, Thapa NM, Pradhan B, Shrestha A, Shrivastav S. Extranodal Natural Killer/T-Cell Lymphoma presenting with Recurrent Nasal Vestibulitis: A Case Report. Nepalese J ENT Head Neck Surg [Internet]. 2026 Jul. 30 [cited 2026 Jul. 30];14(2):20-2. Available from: https://www.njehns.org.np.pradeepbelbase.com.np/index.php/njehns/article/view/275

Issue

Vol. 14 No. 2 (2025)

Section

Case Reports

License

Copyright (c) 2026 Nepalese Journal of ENT Head & Neck Surgery

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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